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Hepatic metabolism contributes to BPC-157 clearance, though the peptide does not appear to undergo extensive first-pass metabolism that would completely prevent oral bioavailability

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Animal Welfare Statement The animal protocol for this study was approved by the Animal Care and Use Committee of Shizuoka Professional University of Agriculture.

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Consequently, designing polymeric micelles in combination with other agents as drug delivery systems can effectively target melanoma cells, impact gene expression, and have high antitumor efficacy