O-FucT-2 Polyclonal Antibody, 100ul Lentiviral Packaging Defects in this gene cause

Defects in this gene cause familial adenomatous polyposis (FAP)

a variant H2A histone that is enriched on inactivated X chromosomes

is exclusively expressed in testis but it has also been found in a wide variety of cancer tissues and cell lines

Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates

Mutations in CHEK2 have been linked with Li-Fraumeni syndrome

O-FucT-2 Polyclonal Antibody, 100ul Lentiviral Packaging Defects in this gene causeFucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) like repeats or thrombospondin (THBS; see MIM 188060) type 1 repeats. POFUT2 is an O fucosyltransferase that use THBS type 1 repeats as substrates (Luo et al. 2006 [PubMed 16464857]).