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These studies are particularly noteworthy given that ferroptosis has recently emerged as an attractive therapeutic target for certain cancers [115]

Autoimmun Rev (2014) 13:398402

Am J Physiol Lung Cell Mol Physiol 307:L597-604

Ferroptosis is readily harnessed in cell culture, where it is induced by GSH depletion (e.g., by erastin) [58] or GPX4 inhibition (e.g., by RSL3) [49] and selectively rescued by potent radical trapping agents (e.g., ferrostatin and liproxstatin, which are not developed for human use) [59, 60]