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E 2 and TH target gene expression are altered by low concentrations of BPA 34 months postexposure It is widely accepted that BPA can exert its effects via classic ER-mediated genomic signaling mechanisms, binding to and activating nuclear ER/ to alter transcription of E 2 -responsive genes

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For BPC-157 specifically, intranasal data remains limited

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References: He L, Feng D, Guo H, Zhou Y, Li Z, Zhang K, Zhang W, Wang S, Wang Z, Hao Q, Zhang C, Gao Y, Gu J, Zhang Y, Li W, Li M

A research study in rats suffering from retinitis pigmentosa demonstrated that the peptide improved results in 90% of cases