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191,192 In vascular endothelial cells, GLP-1R activation stimulates endothelial nitric oxide synthase (eNOS), promoting nitric oxide (NO) production and improving endothelium-dependent vasodilation

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The decrease of antioxidant GSH synthesis could make contributions to oxidative stress that in turn led to increased GSH loss to the extracellular space

The main differences are sample size (smaller for Retatrutide) and duration (shorter for Retatrutide)