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Dejima, K., Kang, S., Mitani, S., Cosman, P

Adequate vitamin D and B vitamins are particularly helpful, Brown says

Others need more time, especially while the dose is being adjusted

Understanding this timeline helps patients maintain realistic expectations and remain committed to therapy during the initial period when changes may seem subtle

However, in patients over 65, those with a history of prediabetes/diabetes, anyone with a cardiovascular disease, and anyone who has been severely overweight should expect to stay on medication forever due to the significant reduction in disability and death

The evidence for this comes from studies in idiopathic intracranial hypertension, a condition characterized by elevated cerebrospinal fluid pressure without a clear structural cause