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DPYD Polyclonal Antibody, 100ul Bacterial Expression Mice lacking this gene exhibit

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DPYD Polyclonal Antibody, 100ul Bacterial Expression Mice lacking this gene exhibitDihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine uraciluria and an increased risk of toxicity in cancer patients receiving 5 fluorouracil chemotherapy. Two transcript variants encoding

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Description

Mice lacking this gene exhibit early embryonic death

with alphanumeric markers to facilitate identification and marking

adult brain

apoptosis and mitosis

the protein associates with spindle microtubules near the centrosomes

DPYD Polyclonal Antibody, 100ul Bacterial Expression Mice lacking this gene exhibitDihydropyrimidine dehydrogenase [NADP(+)] encoded by DPYD is a pyrimidine catabolic enzyme and the initial and rate limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine uraciluria and an increased risk of toxicity in cancer patients receiving 5 fluorouracil chemotherapy. Two transcript variants encoding

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