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PTTG1/2/3 Polyclonal Antibody, 50ul Gloves The gene product complexes with

SKU: 10880835945

4.8
SEK162.00 SEK199.00

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PTTG1/2/3 Polyclonal Antibody, 50ul Gloves The gene product complexes withPituitary tumor transforming 1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase promoting complex (APC) substrate that associates with a separin until activation of the APC. PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. PTTG1 contains 2 PXXP motifs, which are required for its transforming

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Description

The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)

This gene encodes an EFNA class ephrin

It's preferred as it accurately mimics native protein structure and function

Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth

It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs

PTTG1/2/3 Polyclonal Antibody, 50ul Gloves The gene product complexes withPituitary tumor transforming 1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase promoting complex (APC) substrate that associates with a separin until activation of the APC. PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. PTTG1 contains 2 PXXP motifs, which are required for its transforming

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