OAZ2 Polyclonal Antibody, 50ul Cell Culture & Maintenance Two alternatively spliced transcript variants

Two alternatively spliced transcript variants are expressed by the gene

The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities

While conjugates of this protein have been found to be noncovalently attached to intermediate filaments

and exons 6 and 7 encode the cytoplasmic tail

DCK is clinically important because of its relationship to drug resistance and sensitivity

OAZ2 Polyclonal Antibody, 50ul Cell Culture & Maintenance Two alternatively spliced transcript variantsThe protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. This