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RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging This member is the principal

SKU: 11337658741

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RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging This member is the principalRUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions

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Description

This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA)

increased acidification produces increased proteolysis and efficient peptide loading

Histone H2B type 1-H is a core component of nucleosome

each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted

CYP3A43 (cytochrome P450 family 3 subfamily A member 43) encodes a member of the cytochrome P450 superfamily of enzymes

RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging This member is the principalRUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions

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