Dok-2(Phospho Tyr299) Polyclonal Antibody, 50ul Cell Proliferation Mutations in this gene have

Mutations in this gene have been associated with medulloblastomas

The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs)

such as TCR signaling

MOB3B is located on the opposite strand as the interferon kappa precursor (IFNK) gene

Dok-2(Phospho Tyr299) Polyclonal Antibody, 50ul Cell Proliferation Mutations in this gene haveThe protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.