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FXL18 Rabbit Polyclonal Antibody, 100ul Organelle Studies Mutations in this gene are

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FXL18 Rabbit Polyclonal Antibody, 100ul Organelle Studies Mutations in this gene areThe protein encoded by this gene is a member of a family of proteins that contain an approximately 40 amino acid F box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7 a protein that induces mitotic arrest by targeting it for polyubiquitylation and proteasomal degradation. Members of the F box protein family such as FBXL18

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Description

Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1

and multi-channel adjustable models

cholesterol

the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes

FXL18 Rabbit Polyclonal Antibody, 100ul Organelle Studies Mutations in this gene areThe protein encoded by this gene is a member of a family of proteins that contain an approximately 40 amino acid F box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7 a protein that induces mitotic arrest by targeting it for polyubiquitylation and proteasomal degradation. Members of the F box protein family such as FBXL18

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