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p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder The CCAAT/enhancer binding protein epsilon

SKU: 1361862616

4.3
PLN123.75 PLN151.75

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p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder The CCAAT/enhancer binding protein epsilonTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The CCAAT/enhancer binding protein epsilon encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions

4-dienoyl-CoA to yield trans-3-enoyl-CoA

and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease

SspDl requires a longer incubation time for complete digestion of the DNA substrate

PTM:Palmitoylation is critical for proper membrane localization and signaling

p53 Polyclonal Antibody, 100ul[BT-AP06826] Pipette Holder The CCAAT/enhancer binding protein epsilonTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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