TLL2 Rabbit Polyclonal Antibody, 100ul Miscellaneous Mutations in this gene are

Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome

Upregulation of CYSLTR1 is associated with asthma and dysregulation may also be implicated in cancer

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity

Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule

which is encoded by chromosome 15

TLL2 Rabbit Polyclonal Antibody, 100ul Miscellaneous Mutations in this gene areThis gene encodes an astacin like zinc dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members a similar protein in mice does not cleave procollagen C propeptides or chordin.