PCDG9 Rabbit Polyclonal Antibody, 20ul Cell Culture Dishes Knockout studies in mice suggested

Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure

tissue specificity:Found in cerebellum and frontal cortex

This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding

acute myeloid leukemia and malignant lymphomas

The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation

PCDG9 Rabbit Polyclonal Antibody, 20ul Cell Culture Dishes Knockout studies in mice suggestedThis gene is a member of the protocadherin gamma gene cluster one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin like organization suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes subfamily B contains 7 genes and 2 pseudogenes and the more distantly related