Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling subcellular location:Seems to be excluded

subcellular location:Seems to be excluded from nucleoli

The encoded protein (EPS8 like 2)

All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins

or with the remaining 2 exons unique to PEG3

Two protein-coding transcripts and one non-protein coding transcript have been found for this gene

Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling subcellular location:Seems to be excludedThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.