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ATS3 Rabbit Polyclonal Antibody, 20ul Supplements |pharmaceutical:A constitutively active FOXO4 mutant

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ATS3 Rabbit Polyclonal Antibody, 20ul Supplements |pharmaceutical:A constitutively active FOXO4 mutantThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C terminal TS motifs, and some have unique C terminal domains. The encoded

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Description

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

six KID motifs

Binding of insulin or other ligands to this receptor activates the insulin signaling pathway| which regulates glucose uptake and release| as well as the synthesis and storage of carbohydrates| lipids and protein

These subunits play a key role in the plasticity of synapses

The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function

ATS3 Rabbit Polyclonal Antibody, 20ul Supplements |pharmaceutical:A constitutively active FOXO4 mutantThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C terminal TS motifs, and some have unique C terminal domains. The encoded

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