MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification 8kg(O330-M)and speed range 70-400rpm

8kg(O330-M)and speed range 70-400rpm

and may play a catalytic role in the function of the SMN complex on RNPs

a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton

The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins

Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes

MDM2 Polyclonal Antibody, 20ul[BT-AP05301] Purification 8kg(O330-M)and speed range 70-400rpmMDM2 encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many