PIAS 1 Polyclonal Antibody, 50ul Buffers & Solutions This gene is located on

This gene is located on X chromosome in a region containing loci linked to mental retardation

The encoded protein forms a complex with alpha-2

Neuromedin-U is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain

thus may function in signaling pathways utilized broadly during fetal development

Mutations in this gene are associated with ectodermal dysplasia

PIAS 1 Polyclonal Antibody, 50ul Buffers & Solutions This gene is located onPIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript