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HLA-DP Alpha1 Polyclonal Antibody, 20ul Vacuum Aspirator the N-terminal cytoplasmic domain is

SKU: 15642590163

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DKK97.20 DKK129.20

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HLA-DP Alpha1 Polyclonal Antibody, 20ul Vacuum Aspirator the N-terminal cytoplasmic domain isHLA DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33 35 kDa and its

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Description

the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus

and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy

a major nitrosamine specific to tobacco

It acts as a decoy receptor that competes with death receptors for ligand binding

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HLA-DP Alpha1 Polyclonal Antibody, 20ul Vacuum Aspirator the N-terminal cytoplasmic domain isHLA DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33 35 kDa and its

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