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CENPT Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing This gene encodes a non-ATPase

SKU: 16197345470

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CENPT Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing This gene encodes a non-ATPaseThe centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006

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Description

This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins

The encoded protein consists of four N-terminal immunoglobulin-like domains| six fibronectin type III domains| a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC

and transformation

A pseudogene of this gene is also present on chromosome 8q21

CENPT Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing This gene encodes a non-ATPaseThe centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006

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