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Phospho-AP-1 (S63) Polyclonal Antibody, 20ul Low-speed Centrifuges MAD1L1 (MAD1 mitotic arrest deficient

SKU: 16366005689

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Phospho-AP-1 (S63) Polyclonal Antibody, 20ul Low-speed Centrifuges MAD1L1 (MAD1 mitotic arrest deficientJUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto oncogene, AP 1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

MAD1L1 (MAD1 mitotic arrest deficient like 1) is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest

SLC16A2 is expressed in many tissues and likely plays an important role in the development of the central nervous system

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

NMDA receptors are both ligand-gated and voltage-dependent

Phospho-AP-1 (S63) Polyclonal Antibody, 20ul Low-speed Centrifuges MAD1L1 (MAD1 mitotic arrest deficientJUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto oncogene, AP 1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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