SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene can

Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6)

and modulation of cell growth

The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily

The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane

Genetic variation in this gene influences susceptibility to occlusive vascular disease

SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene canSPZ1 (spermatogenic leucine zipper 1) encodes a bHLH zip transcription factor which functions in the mitogen activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, SPZ1 may serve as a target for Ras induced tumor treatments.