PIAS 3 Polyclonal Antibody, 20ul Peptide Library Several pseudogenes of EIF4E are

Several pseudogenes of EIF4E are found on other chromosomes

It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells

The protein (branched chain ketoacid dehydrogenase kinase) encoded by BCKDK is found in the mitochondrion

The promoter polymorphism of IL12B has been reported to be associated with the severity of atopic and non-atopic asthma in children

Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency

PIAS 3 Polyclonal Antibody, 20ul Peptide Library Several pseudogenes of EIF4E arePIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.