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CD47 Polyclonal Antibody, 50ul General Lab Use Important for efficient CD180 cell

SKU: 17809549482

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CD47 Polyclonal Antibody, 50ul General Lab Use Important for efficient CD180 cellCD47 encodes a CD47 molecule, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript

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Description

Important for efficient CD180 cell surface expression

Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis

Multiple transcript variants encoding different isoforms have been found for PTGER3

and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans

tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen(COL1A1) reflecting the different role of alpha2 chains in matrix integrity

CD47 Polyclonal Antibody, 50ul General Lab Use Important for efficient CD180 cellCD47 encodes a CD47 molecule, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript

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