MARCH4 Polyclonal Antibody, 50ul Custom Peptide Synthesis This protein acts as a

This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development

This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation

Alternatively spliced transcript variants have been described| but their biological validity has not been determined

and mRNA export

thereby aiding in host defense through the activation of the lectin pathway

MARCH4 Polyclonal Antibody, 50ul Custom Peptide Synthesis This protein acts as aMARCH4 is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment.