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B23 Polyclonal Antibody, 50ul Drug Development and Evaluation This Tribbles member induces apoptosis

SKU: 17885436005

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B23 Polyclonal Antibody, 50ul Drug Development and Evaluation This Tribbles member induces apoptosisNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin

Cytokine that induces the release of T cell-attracting chemokines from monocytes and| in particular| enhances the maturation of CD11c(+) dendritic cells

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B23 Polyclonal Antibody, 50ul Drug Development and Evaluation This Tribbles member induces apoptosisNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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