ESX1 Rabbit Polyclonal Antibody, 100ul Peripheral Blood Separation Tube CHP1 encodes a phosphoprotein that

CHP1 encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1

A pseudogene of SERPINB9 is found on chromosome 6

The protein can act as an autoantigen in pemphigus diseases

A similar duplicated gene is located next to this gene on chromosome 16

suggesting a role in tumor development and metastasis

ESX1 Rabbit Polyclonal Antibody, 100ul Peripheral Blood Separation Tube CHP1 encodes a phosphoprotein thatThis gene encodes a dual function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N terminal fragment with a paired like homeodomain and a 20 kDa C terminal fragment with a proline rich domain. The C terminal fragment localizes to the cytoplasm while the N terminal fragment localizes exclusively to the nucleus. In contrast to human the mouse homolog has a novel PN PF motif in the C terminus and is paternally imprinted in