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PSPHL Rabbit Polyclonal Antibody, 50ul Cell Culture Plates It is not active until

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PSPHL Rabbit Polyclonal Antibody, 50ul Cell Culture Plates It is not active untilThis gene is significantly upregulated in Fanconi's anemia fibroblasts but downregulated or absent in fibroblasts from normal donors. It is also highly expressed in FA B cells of complementation group A.

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Description

It is not active until the last four amino acids of the carboxy-terminus have been cleaved off

The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins

The DYKDDDDK (FLAG) peptide has been used extensively as a general tag in expression vectors

which suggests a role in the JNK signaling pathway

Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor

PSPHL Rabbit Polyclonal Antibody, 50ul Cell Culture Plates It is not active untilThis gene is significantly upregulated in Fanconi's anemia fibroblasts but downregulated or absent in fibroblasts from normal donors. It is also highly expressed in FA B cells of complementation group A.

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