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PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath CLN5 is one of eight

SKU: 18249032777

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PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath CLN5 is one of eightThis gene encodes a protein that may play a role in pre mRNA splicing. Chromosomal translocations (X; 1)(p11; q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.

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Description

CLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL)

LGR6 encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell

through the regulation of MYPT1 and thus MLC2 phosphorylation

These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen| where they come into contact with| and may be absorbed onto| the sperm membranes

PRCC Rabbit Polyclonal Antibody, 100ul Dry Bath CLN5 is one of eightThis gene encodes a protein that may play a role in pre mRNA splicing. Chromosomal translocations (X; 1)(p11; q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.

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