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GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and Rac guanyl-nucleotide exchange factor activity

The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation

The products encoded by these genes function in signal transduction pathways

subunit:Tetramer composed of an alpha chain

DUSP6 Polyclonal Antibody, 20ul Vacuum Aspirator Unlock your laboratory's potential withThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family