FGFP1 Polyclonal Antibody, 50ul Long RNA Synthesis CBFA2T3 (CBFA2/RUNX1 translocation partner 3)

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression

May act as a GTPase-activating protein of RAB6A

Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis

A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation

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FGFP1 Polyclonal Antibody, 50ul Long RNA Synthesis CBFA2T3 (CBFA2/RUNX1 translocation partner 3)This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic