PDC-E2 Monoclonal Antibody, 100ul Cell Separation and Collection A structurally similar protein has

A structurally similar protein has been found in mouse

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation

The protein encoded by this gene is similar to the yeast Mob1 protein

Some Bartter-like syndromes result from defects in this gene

PDC-E2 Monoclonal Antibody, 100ul Cell Separation and Collection A structurally similar protein hasThis gene encodes component E2 of the multi enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial