Vav(Phospho Tyr160) Polyclonal Antibody, 50ul Cell fragmentation and collection This gene is highly expressed

This gene is highly expressed in fetal tissues and at lower levels in few adult tissues| thus may function in signaling pathways utilized broadly during fetal development| and more selectively in adult tissues

This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule

Binds preferentially single-stranded DNA and unwinds double stranded DNA

and abolishes the suppression of beta-amyloid production by X11L

It is also expressed in specific regions of the brain

Vav(Phospho Tyr160) Polyclonal Antibody, 50ul Cell fragmentation and collection This gene is highly expressedThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.