Frizzled-1 Polyclonal Antibody, 50ul[BT-AP15675] Custom Peptide Synthesis Mutations in this gene are

Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS)| also known as bradyopsia

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

has also been studied because of its expression in human tumors

Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule

which give two distinct kinase activities

Frizzled-1 Polyclonal Antibody, 50ul[BT-AP15675] Custom Peptide Synthesis Mutations in this gene areMembers of the 'frizzled' gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine rich domain in the N terminal extracellular region, 7 transmembrane domains, and a C terminal PDZ domain binding motif. The FZD1 transcript is expressed in various tissues.