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RHXF2 Polyclonal Antibody, 100ul Cell Dissociation Mutations in this gene are

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RHXF2 Polyclonal Antibody, 100ul Cell Dissociation Mutations in this gene areThis gene, which encodes a transcriptional repressor, is one of two paralogous X linked homeobox containing genes and is highly expressed in a variety of cancers. In addition, the encoded protein associates with the cell membrane and with microtubules, and is concentrated at the leading edge of migratory cells.

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Description

Mutations in this gene are associated with neutrophil immunodeficiency syndrome

The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm

The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta

and is required for association with spectrin and actin

The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase

RHXF2 Polyclonal Antibody, 100ul Cell Dissociation Mutations in this gene areThis gene, which encodes a transcriptional repressor, is one of two paralogous X linked homeobox containing genes and is highly expressed in a variety of cancers. In addition, the encoded protein associates with the cell membrane and with microtubules, and is concentrated at the leading edge of migratory cells.

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