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ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation |subunit:When phosphorylated| interacts directly with

SKU: 21178971304

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ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation |subunit:When phosphorylated| interacts directly withThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

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Description

|subunit:When phosphorylated| interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2| GRAP| GRAP2| PLCG1 and PLCG2

Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells

while it has no activity on monomethylated residues

ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation |subunit:When phosphorylated| interacts directly withThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

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