CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette 45 µm Pore Size and

45 µm Pore Size and PES Membrane ensure reliable filtration

This gene is expressed in both normal and tumor cells

It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues

Disruption of this gene has been implicated in Carpenter syndrome as well as cancer

Activated by diacylglycerol (DAG) (By similarity)

CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette 45 µm Pore Size andCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.