TRI11 Rabbit Polyclonal Antibody, 100ul Buffers & Solutions Mutations in this gene have

Mutations in this gene have been identified in aggressive neuroblastomas

Alternate splicing results in multiple transcript variants

The intermediate affinity form consists of an alpha/beta subunit heterodimer

and can be placed at any position

Mutations in PPP2R1B have been associated with some lung and colon cancers

TRI11 Rabbit Polyclonal Antibody, 100ul Buffers & Solutions Mutations in this gene haveThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified.