CD6 Polyclonal Antibody, 50ul[BT-AP02075] Centrifuges May control transcription via direct

May control transcription via direct regulation of the modification of histones and the assembly of chromatin

but shuttles into the nucleus where it localizes to nuclear speckles

The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop

it is a target for cancer therapy

This gene has broad tissue distribution

CD6 Polyclonal Antibody, 50ul[BT-AP02075] Centrifuges May control transcription via directCOL1A2 encodes the pro alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I IV, Ehlers Danlos syndrome type VIIB, recessive Ehlers Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan