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SENP5 Polyclonal Antibody, 100ul Organelle Studies The protein encoded by this

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SENP5 Polyclonal Antibody, 100ul Organelle Studies The protein encoded by thisThe reversible posttranslational modification of proteins by the addition of small ubiquitin like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO

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Description

The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex| which activates pre-mRNA splicing and is an integral part of the spliceosome

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

This gene is intronless and is expressed primarily in the frontal cortex of the brain

galactoside binding soluble 3 is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain

yet they share the same canonical α/β hydrolase fold

SENP5 Polyclonal Antibody, 100ul Organelle Studies The protein encoded by thisThe reversible posttranslational modification of proteins by the addition of small ubiquitin like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO

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