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Pazopanib Catalog No.:M7809-10 Smiles: COC1C=C(C=C(OC)C=1OC)/C=C/C(=O)N1CCN(CC(=O)N2CCCC2)CC1

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Pazopanib Catalog No.:M7809-10 Smiles: COC1C=C(C=C(OC)C=1OC)/C=C/C(=O)N1CCN(CC(=O)N2CCCC2)CC1Pazopanib is an approved drug, is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR) 1, 2 and 3, c kit and platelet derived growth factor receptor (PDGF R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. Check for active clinical trials or closed clinical trials

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Description

Smiles: COC1C=C(C=C(OC)C=1OC)/C=C/C(=O)N1CCN(CC(=O)N2CCCC2)CC1

CAS Number: 2378801-85-3

MK-1775 was orally dosed to mice at 20 mg/Kg once per day

GSK2983559-active metabolite

Pharm Dev Technol

Pazopanib Catalog No.:M7809-10 Smiles: COC1C=C(C=C(OC)C=1OC)/C=C/C(=O)N1CCN(CC(=O)N2CCCC2)CC1Pazopanib is an approved drug, is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR) 1, 2 and 3, c kit and platelet derived growth factor receptor (PDGF R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. Check for active clinical trials or closed clinical trials

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