GIMAP4 Polyclonal Antibody, 50ul Pasteur Pipets Defects in this gene are

Defects in this gene are a cause of polycystic kidney disease (PKD)

converting pyrroline-5-carboxylate to glutamate

Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1

Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity)

Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC

GIMAP4 Polyclonal Antibody, 50ul Pasteur Pipets Defects in this gene areGIMAP4 encodes GTPase IMAP family member 4 belonging to the GTP binding superfamily and to the immuno associated nucleotide (IAN) subfamily of nucleotide binding proteins. GTPase IMAP family member 4 may be negatively regulated by T cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36. 1.