MPPB Rabbit Polyclonal Antibody, 100ul Subcellular Fractions Mutations in this gene cause

Mutations in this gene cause Charcot-Marie-Tooth disease| type 2A1

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such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2)

The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells

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MPPB Rabbit Polyclonal Antibody, 100ul Subcellular Fractions Mutations in this gene causeThis gene is a member of the peptidase M16 family and encodes a protein with a zinc binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria though it only functions as part of a heterodimeric complex.