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Caspase-3 Polyclonal Antibody, 50ul[BT-AP07119] Aspirating Pipets The family member encoded by

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Caspase-3 Polyclonal Antibody, 50ul[BT-AP07119] Aspirating Pipets The family member encoded byThis gene encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the

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Description

The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity| but it is a major target of cell-mediated autoimmunity in diabetes

Exon 1 encodes the leader peptide| exons 2 and 3 encode the two extracellular domains| exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

PMEPA1 encodes a transmembrane protein that contains a Smad interacting motif (SIM)

instead they hold them in large soluble aggregates

hepatic fibrosis or cirrhosis and cardiomyopathy

Caspase-3 Polyclonal Antibody, 50ul[BT-AP07119] Aspirating Pipets The family member encoded byThis gene encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the

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