Med18 Polyclonal Antibody, 50ul Deep Well Plates To date| all members of

To date| all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size| sequence and predicted structure| but differ significantly in their tissue distributions

RPL36 encodes a ribosomal protein that is a component of the 60S subunit

resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair

Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation

Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors

Med18 Polyclonal Antibody, 50ul Deep Well Plates To date| all members ofMED18 is a component of the Mediator complex, which is a coactivator for DNA binding factors that activate transcription via RNA polymerase II.