AIF-M1 Monoclonal Antibody, 50ul Culture Tubes Several alternatively spliced transcript variants

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AIF-M1 Monoclonal Antibody, 50ul Culture Tubes Several alternatively spliced transcript variantsThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. Mutations in this gene cause

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