Tak1(Phospho Thr187) Polyclonal Antibody, 50ul Supplements These studies suggest a role

These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility

sequence-specific DNA binding and RNA polymerase II transcription coactivator activity

Belongs to the PPP phosphatase family

subunit:Interacts with FLII

A neurturin mutation has been described in a family with Hirschsprung Disease

Tak1(Phospho Thr187) Polyclonal Antibody, 50ul Supplements These studies suggest a roleThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP) and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL 1 this protein forms a kinase complex including TRAF6 MAP3K7P1 TAB1 and MAP3K7P2 TAB2; this complex is required for the activation of nuclear factor kappa