TGFBeta RII Polyclonal Antibody, 100ul Erlenmeyer Flasks Sex-determining region Y protein is

Sex-determining region Y protein is the testis-determining factor (TDF)

2000 [PubMed 10799485])

which normally targets nascent secretory peptides to the ER

The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex

Contains 11 LRR (leucine-rich) repeats

TGFBeta RII Polyclonal Antibody, 100ul Erlenmeyer Flasks Sex-determining region Y protein isTGFBR2 encodes a member of the Ser Thr protein kinase family and the TGFB receptor subfamily. The TGF beta receptor type 2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF beta. This receptor ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene