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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use The genomic region is also

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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use The genomic region is alsoLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Description

The genomic region is also rich in Alu repetitive sequences

It is highly conserved in vertebrates and most abundantly expressed in the brain

A pseudogene of this gene has been defined on chromosome 5

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use The genomic region is alsoLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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